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Metabolic research

GLORY-2: extending mazdutide follow-up in Chinese adults

The phase 3 GLORY-2 study randomized Chinese adults with obesity to mazdutide or placebo alongside shared lifestyle support.

Clinical trialPaper year: 2026Mazdutide

01 / DESIGN

What was studied?

The phase 3 GLORY-2 study randomized Chinese adults with obesity to mazdutide or placebo alongside shared lifestyle support.

02 / FINDINGS

What did the researchers report?

The study reported greater sixty-week weight reduction with mazdutide. Gastrointestinal adverse reactions were more frequent in the active-treatment group.

03 / LIMITS

How should it be interpreted?

This population and regimen differ from other mazdutide trials. A weight endpoint does not establish every long-term health outcome, and adverse effects remain part of the interpretation.

Voltera Peptide editorial reading note. Based on the linked source record. Methods and corrections.

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